Fahad Aldosari

Fahad

Fahad's BSc was obtained in Physics at King Saud University in 1998.
During undergraduate study, his interest in physics was strengthened through participating and supervising scientific activities and inventions at schools, which were organised from 1998 to 2013 by the Ministry of Education in Saudi Arabia. During this time, he concentrated on lasers.

While studying for his masters, Fahad focused on Nano-Science, due its great potential for scientific revolutions. Nano-Technology has changed technology in many applications in most areas. This change motivated him to choose "Photoacoustic Properties of Silver Nanoparticles in Solutions" as a masters' dissertation title which he completed in Laser Physics at King Saud University in 2011. Currently, he is working on a PhD with Prof. Francesca Palombo and Prof. Nick Stone within the BioSpec Group.

The subject of the research is Noble metal nanoparticle constructs for Surface-Enhanced Raman Spectroscopy applications in cancer diagnosis and treatment. Generally, my research is focused on the following overall objectives:

  • Prepare the NP constructs accordingly to current protocols
  • Assess the NP suitability for SERS application to cell samples
  • Add Raman reporter to the constructs to investigate cancer targeting

Specifically, the project is aimed at developing biodegradable noble metal nanoparticle constructs based on AuNPs and liposomes (or lipid vesicles) with added SERS activity and tumour-targeting capabilities.

Fahad's University of Exeter Profile

Michelle Bailey

Michelle

Michelle completed her MPhys undergraduate masters degree at the University of Exeter in 2017, with research in Biophysics, studying the diffusion of polymers through gels and cartilage.

Now Michelle is working on her PhD under Prof. Francesca Palombo and Prof. Nick Stone in the BioSpec team. She uses Brillouin microscopy to assess the micromechanical properties of tissues and tissue phantoms, with particular interest in the Biomedical applications of the technique to Oesophageal cancer.

Michelle's University of Exeter Profile

Ioana Blein

Ioana

After a double bachelor’s degree on molecular and cellular biology and on chemistry at the University of Orleans, France, Ioana specialised in chemistry applied to diagnosis and treatment strategy by doing the Master’s degree in Chemistry, Biology and Medication at the University of Strasbourg, France. During that time, she did two internships, both focussing on cancer therapy. One was at the University of Barcelona on a pre-clinical trial of formoterol as a treatment for cancer cachexia. Her second internship in the Faculty of Pharmacy in Strasbourg was on the development of carbon dots as vector for intracellular co-delivery of metformin and a therapeutic siRNA to treat prostate cancer.

In the Biospec group, her PhD work will focus on the synthesis of gold nanoparticles for Surface-Enhanced Raman Spectroscopy (SERS) and photothermal therapy as part of the RaNT project, which aims to develop an all-in-one approach of cancer diagnosis and treatment using gold nanostructures.

Doriana Calabrese

Doriana

Doriana got her master’s degree in Molecular and Industrial Biotechnology at the University of Perugia. During her studies, she became fascinated by the potential and sensitivity of ultrafast non-linear spectroscopy techniques, which led her to complete her master project at the European Laboratory for Non-Linear Spectroscopy (LENS), in Florence. Through that experience, she exploited 2D-IR spectroscopy for studying the dynamical processes of the lipid membranes and calculating the time scale of sub-molecular fluctuation.

Currently, Doriana is enrolled in a PhD under the supervision of Prof. Nick Stone and Prof. Francesca Palombo as a member of Biophysics Group at the University of Exeter. Her research is focused on the application of Raman and FTIR spectroscopies as diagnostic and prognostic tools for the evaluation of breast cancer. This project puts the emphasis on the biochemical heterogeneity of micro-calcifications and their predictive role within the evolution of the tumour.

Doriana's University of Exeter Profile

Diana Frimpong

Diana

Diana Frimpong is a Member of the Royal College of Obstetricians and Gynaecology. She obtained her medical degree in 2012 at the University of Manchester. She is currently a student on the MPhil/PhD programme.

The main objective of her thesis project is to evaluate Raman Spectroscopy both as a diagnostic test for Ovarian Cancer and its discriminatory ability to detect ovarian cancer in post chemotherapy treated tissue.

Jed Spree

Jed

Jed obtained his master’s degree in Physics from the University of Exeter in July 2020 before joining the RaNT team as a PhD student the following November. As an undergraduate his master’s project focused on developing an optical imaging system for detecting microplastic pollution in water.

Under the supervision of Prof Nick Stone and Prof Pavel Matousek, Jed’s PhD project aims to develop and test a novel surface enhanced spatially offset Raman spectroscopy (SESORS) system for the detection, visualisation and treatment of cancers at depths of many centimetres.

Hao Meng

Hao

Hao obtained his master degree of photonics at the University of Jena in Germany in 2021. He worked on a research project of high-pressure Raman gas spectroscopy in Leibniz Institute of Photonic Technology in Jena.

Now Hao joined the BioSpec team as a PhD student from April under the supervision of Prof. Francesca Palombo and Prof. Nick Stone. His PhD project aims to combine Raman and Infrared spectroscopy for biofluid detection of Alzheimer’s disease.